Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0318572
PubChem CID
Molecular Formula
C13H8ClN3O
Molecular Weight
257.68 g/mol
Synonyms/Alias
[CHEMBL2047504; BDBM50420072]
InChI Key
KJPBOPQAFKVBLI-UHFFFAOYSA-N
InChI
InChI=1S/C13H8ClN3O/c14-12-5-4-11(8-16-12)17-13(18)10-3-1-2-9(6-10)7-15/h1-6,8H,(H,17,18)
IUPAC Name
N-(6-chloropyridin-3-yl)-3-cyanobenzamide
CAS Number
1125871-70-6

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

26 27 0 0 0 0 0 0 0 0999 V2000
-3.2720 1.3277 0.6975 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.9424 0.4732 1.5749 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.3336 -0.713...

Experimental Data

Activity Data

Target Ion Channel
Potassium voltage-gated channel subfamily KQT member 2/3
Uniprot Accession Number
Function
Activator
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
EC50: >10000 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
Not mention
Test Method
Efflux Assay ([86] Rubidium Ion)
Test Species
CHO cell (Chinese Hamster Ovary cell)

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
18
Rotatable Bonds
2
logP
2.859
Complexity
68.3572
TPSA (Ų)
65.78
H-Bond Donors
1
H-Bond Acceptors
3
Ring Count
2
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